Pub. Date : 2012 Sep 24
PMID : 22909302
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dopamine D2 receptor-mediated Akt/PKB signalling: initiation by the D2S receptor and role in quinpirole-induced behavioural activation. | Quinpirole | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Dopamine D2 receptor-mediated Akt/PKB signalling: initiation by the D2S receptor and role in quinpirole-induced behavioural activation. | Quinpirole | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | We found that in HEK-293/rD2S cells, the D2/D3 agonists bromocriptine and quinpirole significantly induced Akt and GSK3 phosphorylation, as well as ERK1/2 (extracellular-signal-regulated kinase 1/2) activation. | Quinpirole | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | In addition to our cell culture experiments, we studied D2 receptor-dependent Akt in vivo by systemic administration of the D2/D3 agonist quinpirole. | Quinpirole | AKT serine/threonine kinase 1 | Homo sapiens |
| 5 | The results show that quinpirole evoked Akt-Ser473 phosphorylation in the ventral striatum. | Quinpirole | AKT serine/threonine kinase 1 | Homo sapiens |