Title : CRS-MIS in Candida glabrata: sphingolipids modulate echinocandin-Fks interaction.

Pub. Date : 2012 Oct

PMID : 22909030






1 Functional Relationships(s)
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1 To explore alternative mechanisms, we initially employed Saccharomyces cerevisiae, and observed that CRS was conferred by multiple mutations (fen1Delta, sur4Delta, cka2Delta and tsc10-ts) disrupting sphingolipid biosynthesis. Sphingolipids 3-dehydrosphinganine reductase Saccharomyces cerevisiae S288C