Title : Anti-inflammatory effects of mapracorat, a novel selective glucocorticoid receptor agonist, is partially mediated by MAP kinase phosphatase-1 (MKP-1).

Pub. Date : 2012 Oct 12

PMID : 22898817






1 Functional Relationships(s)
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1 Blocking MKP-1 expression by triptolide also abolished the accelerating effects of mapracorat on p38 and MK-2 deactivation, further supporting a role of MKP-1 in the anti-inflammatory mechanism of mapracorat. triptolide MAPK activated protein kinase 2 Homo sapiens