Pub. Date : 2012 Sep
PMID : 22897577
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have previously shown that the sympathetic nerve cotransmitter adenosine-5"-triphosphate (ATP) and adenosine-5"-O-(3-thio) triphosphate (ATPgammaS), an ATP analogue that is resistant to hydrolysis, increase secretion of the chemokines CXCL8 (interleukin-8), CCL2 (monocyte chemotactic protein-1) and CXCL1 (growth-regulated oncogene alpha) by dermal microvascular ECs. | Adenosine Triphosphate | C-C motif chemokine ligand 2 | Homo sapiens |
| 2 | We have previously shown that the sympathetic nerve cotransmitter adenosine-5"-triphosphate (ATP) and adenosine-5"-O-(3-thio) triphosphate (ATPgammaS), an ATP analogue that is resistant to hydrolysis, increase secretion of the chemokines CXCL8 (interleukin-8), CCL2 (monocyte chemotactic protein-1) and CXCL1 (growth-regulated oncogene alpha) by dermal microvascular ECs. | Adenosine Triphosphate | C-C motif chemokine ligand 2 | Homo sapiens |
| 3 | We have previously shown that the sympathetic nerve cotransmitter adenosine-5"-triphosphate (ATP) and adenosine-5"-O-(3-thio) triphosphate (ATPgammaS), an ATP analogue that is resistant to hydrolysis, increase secretion of the chemokines CXCL8 (interleukin-8), CCL2 (monocyte chemotactic protein-1) and CXCL1 (growth-regulated oncogene alpha) by dermal microvascular ECs. | Adenosine Triphosphate | C-C motif chemokine ligand 2 | Homo sapiens |
| 4 | We have previously shown that the sympathetic nerve cotransmitter adenosine-5"-triphosphate (ATP) and adenosine-5"-O-(3-thio) triphosphate (ATPgammaS), an ATP analogue that is resistant to hydrolysis, increase secretion of the chemokines CXCL8 (interleukin-8), CCL2 (monocyte chemotactic protein-1) and CXCL1 (growth-regulated oncogene alpha) by dermal microvascular ECs. | Adenosine Triphosphate | C-C motif chemokine ligand 2 | Homo sapiens |
| 5 | We have previously shown that the sympathetic nerve cotransmitter adenosine-5"-triphosphate (ATP) and adenosine-5"-O-(3-thio) triphosphate (ATPgammaS), an ATP analogue that is resistant to hydrolysis, increase secretion of the chemokines CXCL8 (interleukin-8), CCL2 (monocyte chemotactic protein-1) and CXCL1 (growth-regulated oncogene alpha) by dermal microvascular ECs. | Adenosine Triphosphate | C-C motif chemokine ligand 2 | Homo sapiens |
| 6 | We have previously shown that the sympathetic nerve cotransmitter adenosine-5"-triphosphate (ATP) and adenosine-5"-O-(3-thio) triphosphate (ATPgammaS), an ATP analogue that is resistant to hydrolysis, increase secretion of the chemokines CXCL8 (interleukin-8), CCL2 (monocyte chemotactic protein-1) and CXCL1 (growth-regulated oncogene alpha) by dermal microvascular ECs. | Adenosine Triphosphate | C-C motif chemokine ligand 2 | Homo sapiens |
| 7 | We have now demonstrated that AFC dose-dependently inhibits ATP-, ATPgammaS- and TNFalpha-induced production of CXCL1, CXCL8 and CCL2 by a human dermal microvascular EC line (HMEC-1) in vitro under conditions that do not affect cell viability. | Adenosine Triphosphate | C-C motif chemokine ligand 2 | Homo sapiens |