Pub. Date : 2012 Sep 1
PMID : 22895185
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | To further investigate the mechanisms underlying these effects, we examined the impact of DACi on the transcription factor c-MYC and the Polycomb group protein BMI1, which are induced by LAFP and involved in leukemic transformation. | daci | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
2 | In AML1/ETO or PLZF/RARalpha-positive 32D cells, DACi-mediated antiproliferative effects were associated with downregulation of BMI1 and c-MYC protein levels. | daci | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |