Title : TWIST1 associates with NF-κB subunit RELA via carboxyl-terminal WR domain to promote cell autonomous invasion through IL8 production.

Pub. Date : 2012 Aug 14

PMID : 22891766






1 Functional Relationships(s)
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1 In this novel mechanism, TWIST1-mediated IL8 transcription is induced through the TWIST1 carboxy-terminal WR (Trp-Arg) domain instead of the classic DNA binding bHLH domain. Tryptophan C-X-C motif chemokine ligand 8 Homo sapiens