Pub. Date : 2012 Nov
PMID : 22891683
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To identify novel therapeutic targets, we recently employed the approach of tandem affinity purification and discovered that calretinin (Cr), a member of the EF-hand family of calcium-binding proteins, is preferentially associated with mHtt, although it also interacts with wild-type Htt. | Calcium | calbindin 2 | Homo sapiens |
| 2 | To identify novel therapeutic targets, we recently employed the approach of tandem affinity purification and discovered that calretinin (Cr), a member of the EF-hand family of calcium-binding proteins, is preferentially associated with mHtt, although it also interacts with wild-type Htt. | Calcium | calbindin 2 | Homo sapiens |
| 3 | In addition, over-expression of Cr was also associated with reduction of intracellular free calcium and activation of Akt. | Calcium | calbindin 2 | Homo sapiens |