Title : Distinct mechanisms of endocrine disruption of DDT-related pesticides toward estrogen receptor α and estrogen-related receptor γ.

Pub. Date : 2012 Nov

PMID : 22890857






1 Functional Relationships(s)
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1 Molecular dynamics (MD) simulations were applied to probe the molecular recognition process of DDT and its five analogs, including dichlordiphenyldichloroethylene (DDE), dichlorodiphenyldichloroethane (DDD), methoxychlor (MXC), p,p"-hydroxy-DDT (HPTE), and dicofol by human estrogen receptor (ER) alpha and human ER-related receptor (ERR) gamma. DDT estrogen related receptor gamma Homo sapiens