Title : [Expression of lymphokines in CD8(+)HLA-DR(+) T lymphocytes of patients with severe aplastic anemia].

Pub. Date : 2012 May 15

PMID : 22883060






3 Functional Relationships(s)
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1 METHODS: The CD8(+)HLA-DR(+) cells were sorted by immunomagnetic separation from the PB of 24 untreated SAA patients and 23 normal controls. saa CD8a molecule Homo sapiens
2 The mRNA level of FasL in CD8(+)HLA-DR(+) T cells of untreated SAA patients was higher than that of the controls (0.77 +- 0.24 vs 0.61 +- 0.16, P = 0.011). saa CD8a molecule Homo sapiens
3 The mRNA of TNF-beta in CD8(+)HLA-DR(+) T cells of untreated SAA patients was also higher than that of the controls (0.58 +- 0.16 vs 0.46 +- 0.15, P = 0.011). saa CD8a molecule Homo sapiens