Title : The adenosine A3 receptor agonist Cl-IB-MECA induces cell death through Ca²⁺/ROS-dependent down regulation of ERK and Akt in A172 human glioma cells.

Pub. Date : 2012 Dec

PMID : 22878643






1 Functional Relationships(s)
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1 Western blot analysis showed that CI-IB-MECA induced the down-regulation of extracellular signal-regulated kinases (ERK) and Akt, which was prevented by EGTA, NAC, and the A3AR antagonist MRS1191. Acetylcysteine AKT serine/threonine kinase 1 Homo sapiens