Pub. Date : 2012 Sep 4
PMID : 22853447
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides. | Dipeptides | solute carrier family 36 member 1 | Homo sapiens |
| 2 | Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides. | Dipeptides | solute carrier family 36 member 1 | Homo sapiens |
| 3 | The aim of the present study is to investigate if other Gly-containing dipeptides interact with PAT1, and whether they can inhibit PAT1 mediated drug absorption, in vitro and in vivo. | Dipeptides | solute carrier family 36 member 1 | Homo sapiens |
| 4 | In conclusion, the present study identifies selected dipeptides as inhibitors of PAT1 mediated drug absorption in various in vitro models. | Dipeptides | solute carrier family 36 member 1 | Homo sapiens |