Title : Skin tumours induced by narrowband UVB have higher frequency of p53 mutations than tumours induced by broadband UVB independent of Ogg1 genotype.

Pub. Date : 2012 Nov

PMID : 22844076






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Most of the p53 mutations found were G:C A:T transitions at dipyrimidine sites in both the NB-UVB- and BB-UVB-exposed groups. dipyrimidine transformation related protein 53, pseudogene Mus musculus
2 Our results strongly suggest that NB-UVB induces highly malignant tumours caused by p53 dipyrimidine mutations through the formation of CPDs. dipyrimidine transformation related protein 53, pseudogene Mus musculus