Pub. Date : 1990 Fall
PMID : 2284053
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Acetylcholinesterase and neuropathy target esterase in chickens treated with acephate. | acephate | acetylcholinesterase (Cartwright blood group) | Gallus gallus |
| 2 | Regression analyses indicated an ID50 (a dose that inhibits 50% of activity) for acephate inhibition of AChE of 10 mg/kg and an extrapolated ID50 for inhibition of NTE of 1300 mg/kg, almost twice the LD50. | acephate | acetylcholinesterase (Cartwright blood group) | Gallus gallus |
| 3 | The results show acephate is a more potent inhibitor of AChE than it is of NTE in hens and suggest it would be difficult to administer a single dose of acephate sufficient to cause OPIDN without killing the animal. | acephate | acetylcholinesterase (Cartwright blood group) | Gallus gallus |