Pub. Date : 2012 Dec
PMID : 22828274
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Fingolimod inhibits PDGF-B-induced migration of vascular smooth muscle cell by down-regulating the S1PR1/S1PR3 pathway. | Fingolimod Hydrochloride | sphingosine-1-phosphate receptor 3 | Rattus norvegicus |
| 2 | Fingolimod induced a 50% reduction in S1PR3 protein expression which was cumulative with that obtained with anti-S1PR3 siRNA. | Fingolimod Hydrochloride | sphingosine-1-phosphate receptor 3 | Rattus norvegicus |
| 3 | Fingolimod induced a 50% reduction in S1PR3 protein expression which was cumulative with that obtained with anti-S1PR3 siRNA. | Fingolimod Hydrochloride | sphingosine-1-phosphate receptor 3 | Rattus norvegicus |
| 4 | As an S1P analogue, fingolimod is considered a potent activator of S1PR1 and S1PR3. | Fingolimod Hydrochloride | sphingosine-1-phosphate receptor 3 | Rattus norvegicus |