Pub. Date : 2012 Oct
PMID : 22822047
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | DPP4 inhibitor vildagliptin preserves beta-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice. | Vildagliptin | CCAAT/enhancer binding protein (C/EBP), beta | Mus musculus |
2 | The expression of C/EBPB protein, but not mRNA, was unexpectedly downregulated in vildagliptin-treated TG mice and in exenatide-treated MIN6 cells. | Vildagliptin | CCAAT/enhancer binding protein (C/EBP), beta | Mus musculus |
3 | Vildagliptin elicits protective effects on pancreatic beta cells, possibly through C/EBPB degradation, and has potential for preventing the progression of type 2 diabetes. | Vildagliptin | CCAAT/enhancer binding protein (C/EBP), beta | Mus musculus |