Title : DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice.

Pub. Date : 2012 Oct

PMID : 22822047






3 Functional Relationships(s)
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Protein Name
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1 DPP4 inhibitor vildagliptin preserves beta-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice. Vildagliptin CCAAT/enhancer binding protein (C/EBP), beta Mus musculus
2 The expression of C/EBPB protein, but not mRNA, was unexpectedly downregulated in vildagliptin-treated TG mice and in exenatide-treated MIN6 cells. Vildagliptin CCAAT/enhancer binding protein (C/EBP), beta Mus musculus
3 Vildagliptin elicits protective effects on pancreatic beta cells, possibly through C/EBPB degradation, and has potential for preventing the progression of type 2 diabetes. Vildagliptin CCAAT/enhancer binding protein (C/EBP), beta Mus musculus