Pub. Date : 2012 Dec 21
PMID : 22818786
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effect of inhibitors of histone deacetylase (HDAC) on Apicomplexa has been previously reported with the discovery of apicidin, a cyclic tetrapeptide having broad-spectrum antiparasitic activity. | apicidin | histone deacetylase 9 | Homo sapiens |
| 2 | The lower IC(50) values of apicidin against apicomplexan parasites than those of mammalian cells point to HDAC as an excellent drug target. | apicidin | histone deacetylase 9 | Homo sapiens |