Title : Stereoselective glucuronidation of carvedilol in human liver and intestinal microsomes.

Pub. Date : 2012

PMID : 22814440






2 Functional Relationships(s)
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1 BACKGROUND AND PURPOSE: Carvedilol is used clinically as a beta-adrenoceptor antagonist for the treatment of chronic heart failure and is primarily metabolized into glucuronides by UDP-glucuronosyltransferase (UGT). Glucuronides UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens
2 BACKGROUND AND PURPOSE: Carvedilol is used clinically as a beta-adrenoceptor antagonist for the treatment of chronic heart failure and is primarily metabolized into glucuronides by UDP-glucuronosyltransferase (UGT). Glucuronides UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens