Title : Inhibition of endoplasmic reticulum stress improves mouse embryo development.

Pub. Date : 2012

PMID : 22808162






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Tunicamycin (TM), an ER stress inducer used as a positive control, promoted an increase in the density of nuclear XBP-1 at the one-cell and two-cell stages. Tunicamycin X-box binding protein 1 Mus musculus
2 Conversely, high concentrations of TM or sorbitol led to reduced nuclear XBP-1 density and significant ER stress-induced apoptosis. Tunicamycin X-box binding protein 1 Mus musculus