Title : [Effects of ursolic acid in ameliorating insulin resistance in liver of KKAy mice via peroxisome proliferator-activated receptors α and γ].

Pub. Date : 2012 Jul

PMID : 22805086






1 Functional Relationships(s)
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1 CONCLUSION: The effects of ursolic acid in improving hepatic insulin resistance in KKAy mice with spontaneous type 2 diabetes may be closely related to affecting the contents of FFA, TNF-alpha and adiponectin, improving the expression of PPARalpha protein, regulating transcription of PEPCK protein and inducing phosphorylation of IRS-2. ursolic acid adiponectin, C1Q and collagen domain containing Mus musculus