Title : Selective non-lipid modulator of LPA5 activity in human platelets.

Pub. Date : 2012 Aug 15

PMID : 22801643






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Recently, the G protein-coupled receptor LPA5/GPR92 has been identified to be the relevant LPA receptor responsible for the activation of human platelets by LPA. lysophosphatidic acid lysophosphatidic acid receptor 5 Homo sapiens
2 We could confirm using antagonists for alternative LPA receptors that we identified in our work the first non-lipid, small-molecule inhibitor for LPA5/GPR92 specifically inhibiting LPA-mediated platelet activation in vitro. lysophosphatidic acid lysophosphatidic acid receptor 5 Homo sapiens
3 We could confirm using antagonists for alternative LPA receptors that we identified in our work the first non-lipid, small-molecule inhibitor for LPA5/GPR92 specifically inhibiting LPA-mediated platelet activation in vitro. lysophosphatidic acid lysophosphatidic acid receptor 5 Homo sapiens