Title : Abnormal conformation and impaired degradation of propylthiouracil-induced neutrophil extracellular traps: implications of disordered neutrophil extracellular traps in a rat model of myeloperoxidase antineutrophil cytoplasmic antibody-associated vasculitis.

Pub. Date : 2012 Nov

PMID : 22777766






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1 Abnormal conformation and impaired degradation of propylthiouracil-induced neutrophil extracellular traps: implications of disordered neutrophil extracellular traps in a rat model of myeloperoxidase antineutrophil cytoplasmic antibody-associated vasculitis. Propylthiouracil myeloperoxidase Rattus norvegicus
2 Propylthiouracil (PTU), an antithyroid drug, is associated with a risk of MPO antineutrophil cytoplasmic antibody (ANCA) production and MPO ANCA-associated vasculitis (MPO AAV). Propylthiouracil myeloperoxidase Rattus norvegicus
3 Propylthiouracil (PTU), an antithyroid drug, is associated with a risk of MPO antineutrophil cytoplasmic antibody (ANCA) production and MPO ANCA-associated vasculitis (MPO AAV). Propylthiouracil myeloperoxidase Rattus norvegicus
4 Propylthiouracil (PTU), an antithyroid drug, is associated with a risk of MPO antineutrophil cytoplasmic antibody (ANCA) production and MPO ANCA-associated vasculitis (MPO AAV). Propylthiouracil myeloperoxidase Rattus norvegicus
5 Propylthiouracil (PTU), an antithyroid drug, is associated with a risk of MPO antineutrophil cytoplasmic antibody (ANCA) production and MPO ANCA-associated vasculitis (MPO AAV). Propylthiouracil myeloperoxidase Rattus norvegicus
6 Propylthiouracil (PTU), an antithyroid drug, is associated with a risk of MPO antineutrophil cytoplasmic antibody (ANCA) production and MPO ANCA-associated vasculitis (MPO AAV). Propylthiouracil myeloperoxidase Rattus norvegicus
7 Propylthiouracil (PTU), an antithyroid drug, is associated with a risk of MPO antineutrophil cytoplasmic antibody (ANCA) production and MPO ANCA-associated vasculitis (MPO AAV). Propylthiouracil myeloperoxidase Rattus norvegicus
8 This study was undertaken to clarify the mechanism of MPO ANCA production, using the PTU-induced model of MPO AAV. Propylthiouracil myeloperoxidase Rattus norvegicus
9 This study was undertaken to clarify the mechanism of MPO ANCA production, using the PTU-induced model of MPO AAV. Propylthiouracil myeloperoxidase Rattus norvegicus
10 When rats were given oral PTU with intraperitoneal injection of PMA, pauci-immune glomerulonephritis and pulmonary capillaritis occurred with MPO ANCA production in the serum. Propylthiouracil myeloperoxidase Rattus norvegicus