Pub. Date : 2012 Aug
PMID : 22764054
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway. | Carotenoids | beta-carotene oxygenase 2 | Homo sapiens |
| 2 | Moreover, BCDO2 prevented this induction of the apoptotic pathway by carotenoids. | Carotenoids | beta-carotene oxygenase 2 | Homo sapiens |
| 3 | Thus, our study identifying BCDO2 as a crucial protective component against oxidative stress establishes this enzyme as mitochondrial carotenoid scavenger and a gatekeeper of the intrinsic apoptotic pathway. | Carotenoids | beta-carotene oxygenase 2 | Homo sapiens |