Title : Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR).

Pub. Date : 2012 Sep 14

PMID : 22761424






4 Functional Relationships(s)
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1 Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR). Polycyclic Aromatic Hydrocarbons ATP-binding cassette, sub-family B (MDR/TAP), member 6 Mus musculus
2 Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR). Polycyclic Aromatic Hydrocarbons ATP-binding cassette, sub-family B (MDR/TAP), member 6 Mus musculus
3 In the present study, we demonstrate that polycyclic aromatic hydrocarbons (PAHs), the widely distributed environmental toxicants shown to induce porphyrin accumulation causing hepatic porphyria, up-regulate ABCB6 expression in both mice and humans. Polycyclic Aromatic Hydrocarbons ATP-binding cassette, sub-family B (MDR/TAP), member 6 Mus musculus
4 In the present study, we demonstrate that polycyclic aromatic hydrocarbons (PAHs), the widely distributed environmental toxicants shown to induce porphyrin accumulation causing hepatic porphyria, up-regulate ABCB6 expression in both mice and humans. Polycyclic Aromatic Hydrocarbons ATP-binding cassette, sub-family B (MDR/TAP), member 6 Mus musculus