Title : Activation of the transcription factor carbohydrate-responsive element-binding protein by glucose leads to increased pancreatic beta cell differentiation in rats.

Pub. Date : 2012 Oct

PMID : 22760788






3 Functional Relationships(s)
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1 Activation of the transcription factor carbohydrate-responsive element-binding protein by glucose leads to increased pancreatic beta cell differentiation in rats. Glucose MLX interacting protein-like Rattus norvegicus
2 When rat embryonic pancreases were cultured in the presence of glucose or xylitol, the production of ChREBP targets was induced. Glucose MLX interacting protein-like Rattus norvegicus
3 CONCLUSIONS/INTERPRETATION: Our work supports the idea that glucose, through the transcription factor ChREBP, controls beta cell differentiation from pancreatic progenitors. Glucose MLX interacting protein-like Rattus norvegicus