Title : Dissecting mammalian target of rapamycin to promote longevity.

Pub. Date : 2012 Jun

PMID : 22758368






1 Functional Relationships(s)
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1 Adenosine monophosphate kinase (AMPK) agonists such as metformin, which inhibits gluconeogenesis by downregulating expression of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase, might be expected to block the glucose dysmetabolism mediated by rapamycin. Metformin glucose-6-phosphatase catalytic subunit 1 Homo sapiens