Pub. Date : 2013 May 23
PMID : 22751115
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | AMPK activation by its activators AICAR (5-aminoimidazole-4-carboxamide ribonucleoside) and metformin (N",N"-dimethylbiguanide), the most widely used antidiabetic drug, increased the expression of XPC and UVB-induced DNA repair in mouse skin, normal human epidermal keratinocytes, and AMPK wild-type (WT) cells but not in AMPK-deficient cells, indicating an AMPK-dependent mechanism. | Metformin | xeroderma pigmentosum, complementation group C | Mus musculus |
| 2 | AMPK activation by its activators AICAR (5-aminoimidazole-4-carboxamide ribonucleoside) and metformin (N",N"-dimethylbiguanide), the most widely used antidiabetic drug, increased the expression of XPC and UVB-induced DNA repair in mouse skin, normal human epidermal keratinocytes, and AMPK wild-type (WT) cells but not in AMPK-deficient cells, indicating an AMPK-dependent mechanism. | Metformin | xeroderma pigmentosum, complementation group C | Mus musculus |