Title : Lipid raft disruption by docosahexaenoic acid induces apoptosis in transformed human mammary luminal epithelial cells harboring HER-2 overexpression.

Pub. Date : 2013 Mar

PMID : 22749134






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1 In HB4aC5.2 cells, but not HB4a cells, we found that DHA treatment disrupted lipid raft; inhibited HER-2 signaling by decreasing activation of Akt, ERK1/2 and FASN proteins; and induced apoptosis. Docosahexaenoic Acids AKT serine/threonine kinase 1 Homo sapiens