Title : BRCA1-dependent Chk1 phosphorylation triggers partial chromatin disassociation of phosphorylated Chk1 and facilitates S-phase cell cycle arrest.

Pub. Date : 2012 Nov

PMID : 22743332






1 Functional Relationships(s)
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1 Here we report that BRCA1 is critical for Chk1 phosphorylation in response to inhibition of replication by either cisplatin or hydroxyurea. Cisplatin checkpoint kinase 1 Homo sapiens