Title : Potentially estrogenic polychlorinated biphenyls congeners serum levels and its relation with lung cancer.

Pub. Date : 2013 Sep

PMID : 22729568






1 Functional Relationships(s)
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1 The high levels of PCB with estrogenic activity found in our cases, could promote lung cancer inducing cell proliferation in non-neoplastic and neoplastic lung cells via ERbeta; inducing the formation of DNA adducts, producing oxidative stress with the subsequent DNA damage and increasing the endogenous catechol levels by catechol-O-methyl transferase (COMT) inhibition. catechol pyruvate carboxylase Homo sapiens