Pub. Date : 2013 Feb
PMID : 22727944
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study demonstrates that serine palmitoyltransferase (SPT) in the astrocytes increases ceramide levels, which enhances the release of cytokines that mediate the activation of neural and acidic sphingomyelinase (SMase) in the neurons, to propagate the deleterious effects of PA (i.e., BACE1 upregulation). | Ceramides | alanine--glyoxylate and serine--pyruvate aminotransferase | Rattus norvegicus |
| 2 | This study demonstrates that serine palmitoyltransferase (SPT) in the astrocytes increases ceramide levels, which enhances the release of cytokines that mediate the activation of neural and acidic sphingomyelinase (SMase) in the neurons, to propagate the deleterious effects of PA (i.e., BACE1 upregulation). | Ceramides | alanine--glyoxylate and serine--pyruvate aminotransferase | Rattus norvegicus |