Title : Rac-ing to the plasma membrane: the long and complex work commute of Rac1 during cell signaling.

Pub. Date : 2012 Jan-Mar

PMID : 22714419






1 Functional Relationships(s)
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1 The functional cycle of the Rac1 GTPase involves a large number of steps, including post-translational processing, cytosolic sequestration by RhoGDIs, translocation to specific subcellular localizations, activation by GDP/GTP exchange, inactivation by GTP hydrolysis, and re-formation of cytosolic Rac1/RhoGDI inhibitory complexes. Guanosine Diphosphate Rac family small GTPase 1 Homo sapiens