Title : The liver-specific tumor suppressor STAT5 controls expression of the reactive oxygen species-generating enzyme NOX4 and the proapoptotic proteins PUMA and BIM in mice.

Pub. Date : 2012 Dec

PMID : 22711600






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Besides suppressing the activation of STAT3, STAT5 induces the expression of proapoptotic genes and the production of ROS. Reactive Oxygen Species signal transducer and activator of transcription 3 Mus musculus