Pub. Date : 2012 Aug
PMID : 22694979
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | RESULTS: Treatment with simvastatin resulted in a decrease in 4-HNE and TNF-alpha concentration (median 4.18 mug/mg protein vs. 4.75, p = 0.012; median 10.33 pg/ml vs. 11.81, p = 0.026, respectively). | Simvastatin | tumor necrosis factor | Homo sapiens |
2 | CONCLUSION: Simvastatin inhibits free radicals and TNF-alpha generation and improves antioxidant capacity of human AAA wall tissue, possibly through the suppression of NF-kappaB activity. | Simvastatin | tumor necrosis factor | Homo sapiens |