Pub. Date : 2012 Jun
PMID : 22684553
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In this study we investigated the activated state of a pathway, in which reactive oxygen species (ROS) induces cellular senescence through DNA damage and phophorylation of p38 MAPK (p38), in myeloid leukemic CD34(+)CD38(-) cells. | Reactive Oxygen Species | CD38 molecule | Homo sapiens |
2 | In this study we investigated the activated state of a pathway, in which reactive oxygen species (ROS) induces cellular senescence through DNA damage and phophorylation of p38 MAPK (p38), in myeloid leukemic CD34(+)CD38(-) cells. | Reactive Oxygen Species | CD38 molecule | Homo sapiens |
3 | Our results showed that ROS and DNA damage were substantially accumulated and p38 was less phosphorated in myeloid leukemic CD34(+)CD38(-) cells as compared with HSCs and H(2)O(2)-induced senescent HSCs. | Reactive Oxygen Species | CD38 molecule | Homo sapiens |