Title : Silencing of the Il2 gene transcription is regulated by epigenetic changes in anergic T cells.

Pub. Date : 2012 Sep

PMID : 22684523






2 Functional Relationships(s)
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1 We had previously shown that in anergic CD4(+) T cells, Ikaros participates in the transcriptional repression of the Il2 gene by recruiting histone deacetylases that cause core histone deacetylation at the Il2 promoter. ikaros interleukin 2 Homo sapiens
2 We had previously shown that in anergic CD4(+) T cells, Ikaros participates in the transcriptional repression of the Il2 gene by recruiting histone deacetylases that cause core histone deacetylation at the Il2 promoter. ikaros interleukin 2 Homo sapiens