Title : The different induction mechanisms of growth arrest DNA damage inducible gene 45 β in human hepatoma cell lines.

Pub. Date : 2012

PMID : 22678405






2 Functional Relationships(s)
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1 METHODS: Following our published data from S-adenosylmethionine (SAMe), oxaliplatin and sorafenib were further used to stimulate GADD45beta expression in cultured HepG2 (p53 wild type) and Hep3B (p53 null) hepatoma cells in vitro. Sorafenib growth arrest and DNA damage inducible beta Homo sapiens
2 RESULTS: Oxaliplatin and sorafenib could induce GADD45beta in both HepG2 and Hep3B in a dose-dependent manner with rapid and direct cytotoxic effect. Sorafenib growth arrest and DNA damage inducible beta Homo sapiens