Title : Aflatoxin-induced TP53 R249S mutation in hepatocellular carcinoma in Thailand: association with tumors developing in the absence of liver cirrhosis.

Pub. Date : 2012

PMID : 22675488






2 Functional Relationships(s)
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1 Aflatoxin-induced TP53 R249S mutation in hepatocellular carcinoma in Thailand: association with tumors developing in the absence of liver cirrhosis. Aflatoxins tumor protein p53 Homo sapiens
2 Most HCC are associated with chronic infection by Hepatitis B Virus while a G T mutation at codon 249 of the TP53 gene, R249S, specific for exposure to aflatoxin, is detected in tumors for up to 30% of cases. Aflatoxins tumor protein p53 Homo sapiens