Title : Thrombin induces epidermal growth factor receptor transactivation and CCL2 expression in human osteoblasts.

Pub. Date : 2012 Oct

PMID : 22674286






1 Functional Relationships(s)
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1 Thrombin-mediated CCL2 production was attenuated by the thrombin inhibitor PPACK, the protein kinase Cdelta (PKCdelta) inhibitor rottlerin, the c-Src inhibitor PP2, epidermal growth factor receptor (EGFR) inhibitor AG-1478, MEK inhibitors PD98059 and U0126, or AP-1 inhibitors curcumin and tanshinone IIA. Curcumin C-C motif chemokine ligand 2 Homo sapiens