Title : Galantamine, an acetylcholinesterase inhibitor and positive allosteric modulator of nicotinic acetylcholine receptors, attenuates nicotine taking and seeking in rats.

Pub. Date : 2012 Sep

PMID : 22669169






1 Functional Relationships(s)
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1 These results indicate that increased extracellular acetylcholine levels and/or nicotinic acetylcholine receptor stimulation is sufficient to attenuate nicotine taking and seeking in rats and that these effects are reinforcer selective and not due to adverse malaise symptoms such as nausea. Nicotine cholinergic receptor nicotinic alpha 2 subunit Rattus norvegicus