Title : Beta-glucosidase 1 (GBA1) is a second bile acid β-glucosidase in addition to β-glucosidase 2 (GBA2). Study in β-glucosidase deficient mice and humans.

Pub. Date : 2012 Jun 29

PMID : 22659419






2 Functional Relationships(s)
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Protein Name
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1 Beta-glucosidase 1 (GBA1; lysosomal glucocerebrosidase) and beta-glucosidase 2 (GBA2, non-lysosomal glucocerebrosidase) both have glucosylceramide as a main natural substrate. Glucosylceramides glucosidase, beta, acid Mus musculus
2 Given that GBA2 hydrolyses both BG and glucosylceramide, it was asked whether vice versa GBA1 hydrolyses both glucosylceramide and BG. Glucosylceramides glucosidase, beta, acid Mus musculus