Pub. Date : 2012 Oct
PMID : 22644804
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The results revealed that high glucose promoted the splicing of XBP-1, concomitant with up-regulation of lipogenic genes including fatty acid synthase, acetyl-CoA carboxylase, adipocyte differentiation-related protein, and cellular triglyceride. | Triglycerides | X-box binding protein 1 | Homo sapiens |
| 2 | Furthermore, we confirmed that the inhibition of phosphotidyl inositol 3-kinase (PI3K)/Akt pathway with LY294002 or Akt shRNA vector blocked the effect of high glucose on XBP-1 splicing and cellular triglyceride. | Triglycerides | X-box binding protein 1 | Homo sapiens |