Title : Click chemistry-derived bivalent quinine inhibitors of P-glycoprotein-mediated cellular efflux.

Pub. Date : 2012 Jul 1

PMID : 22632934






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1 Herein we demonstrate the use of click chemistry to rapidly generate bivalent quinine dimers, containing an intervening triazole ring, as potential inhibitors of P-gp mediated efflux. Quinine phosphoglycolate phosphatase Homo sapiens