Title : Androgen initiates Sertoli cell tight junction formation in the hypogonadal (hpg) mouse.

Pub. Date : 2012 Aug

PMID : 22623623






2 Functional Relationships(s)
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1 In hpg testes, DHT treatment stimulated the redistribution of claudin-11 protein toward the basal region of Sertoli cells by Day 2, increased Cldn3 and Cldn11 mRNA expression, then induced the formation of functional TJs containing both proteins by Day 10. Dihydrotestosterone gonadotropin releasing hormone 1 Mus musculus
2 In hpg+tgFSH testes, TJ protein redistribution was accelerated and functional TJs formed by Day 2 of DHT treatment. Dihydrotestosterone gonadotropin releasing hormone 1 Mus musculus