Title : Meloxicam ameliorates motor dysfunction and dopaminergic neurodegeneration by maintaining Akt-signaling in a mouse Parkinson's disease model.

Pub. Date : 2012 Jul 11

PMID : 22617635






1 Functional Relationships(s)
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1 Concomitant decreases of TH protein levels in the striatum and midbrain of MPTP/MLX-treated mice were not only significantly (p<0.01 and p<0.05, respectively) ameliorated but phosphorylated Akt (pAkt473) expression in the midbrain was also significantly (p<0.01) increased in the midbrain when compared with MPTP/saline-treated mice. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine thymoma viral proto-oncogene 1 Mus musculus