Title : Usefulness of administration of non-organophosphate cholinesterase inhibitors before acute exposure to organophosphates: assessment using paraoxon.

Pub. Date : 2013 Sep

PMID : 22611016






1 Functional Relationships(s)
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1 Best in vivo protection from paraoxon-induced mortality was observed after prophylactic administration of physostigmine (RR = 0.30) or the oxime K-27 (RR = 0.34); both treatments were significantly superior to the pre-treatment with all other tested compounds, including the established substance pyridostigmine. Pyridostigmine Bromide keratin 27 Rattus norvegicus