Pub. Date : 2012 Jul
PMID : 22610166
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tumor promoter treatment induces the rate-limiting enzymes in polyamine biosynthesis, ornithine decarboxylase (ODC), and S-adenosylmethionine decarboxylase (AdoMetDC), and targeted ODC overexpression is sufficient for tumor promotion in initiated mouse skin. | Polyamines | S-adenosylmethionine decarboxylase 1 | Mus musculus |
| 2 | AdoMetDC-expressing mice will enable more refined spatial and temporal manipulation of polyamine biosynthesis during tumorigenesis and in other models of human disease. | Polyamines | S-adenosylmethionine decarboxylase 1 | Mus musculus |