Title : Mutations of the mitochondrial-tRNA modifier MTO1 cause hypertrophic cardiomyopathy and lactic acidosis.

Pub. Date : 2012 Jun 8

PMID : 22608499






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 In both humans and yeast, MTO1 increases the accuracy and efficiency of mtDNA translation by catalyzing the 5-carboxymethylaminomethylation of the wobble uridine base in three mitochondrial tRNAs (mt-tRNAs). Uridine tRNA modification protein MTO1 Saccharomyces cerevisiae S288C