Pub. Date : 2012 Aug
PMID : 22593037
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Potent inhibition of human sulfotransferase 1A1 by 17alpha-ethinylestradiol: role of 3"-phosphoadenosine 5"-phosphosulfate binding and structural rearrangements in regulating inhibition and activity. | Phosphoadenosine Phosphosulfate | sulfotransferase family 1A member 1 | Homo sapiens |
| 2 | The K(d) for E2 binding to SULT1A1 changed from 2.3 +- 0.9 to 1.2 +- 0.56 muM in the presence of PAP. | Phosphoadenosine Phosphosulfate | sulfotransferase family 1A member 1 | Homo sapiens |
| 3 | Docking studies with E2 indicate that E2 binds in a competent orientation in the resolved structure of SULT1A1 in the both presence and absence of 3"-phosphoadenosine 5"-phosphosulfate (PAPS). | Phosphoadenosine Phosphosulfate | sulfotransferase family 1A member 1 | Homo sapiens |
| 4 | Docking studies with E2 indicate that E2 binds in a competent orientation in the resolved structure of SULT1A1 in the both presence and absence of 3"-phosphoadenosine 5"-phosphosulfate (PAPS). | Phosphoadenosine Phosphosulfate | sulfotransferase family 1A member 1 | Homo sapiens |