Title : Redox properties and thiol reactivity of geldanamycin and its analogues in aqueous solutions.

Pub. Date : 2012 Jun 7

PMID : 22591491






1 Functional Relationships(s)
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1 Using pulse radiolysis, the one-electron redox potentials (vs NHE) at pH 7.0 of GM and 17-AAG have been determined to be -62 +- 7 mV and -273 +- 8 mV, respectively, whereas a value of -194 +- 6 mV has been previously published for 17-DMAG. tanespimycin solute carrier family 9 member C1 Homo sapiens