Pub. Date : 2012 Nov
PMID : 22581436
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PYK-2 is tyrosine phosphorylated after activation of pituitary adenylate cyclase activating polypeptide receptors in lung cancer cells. | Tyrosine | protein tyrosine kinase 2 beta | Homo sapiens |
| 2 | In this communication, the effects of PACAP on cytosolic Ca(2+) and PYK-2 tyrosine phosphorylation were investigated. | Tyrosine | protein tyrosine kinase 2 beta | Homo sapiens |
| 3 | PACAP-38, but not vasoactive intestinal peptide (VIP), addition to NCI-H838 or H1299 cells significantly increased the tyrosine phosphorylation of PYK-2 after 2 min. | Tyrosine | protein tyrosine kinase 2 beta | Homo sapiens |
| 4 | The increase in PYK-2 tyrosine phosphorylation caused by PACAP was inhibited by PACAP(6-38), U73122, or BAPTA, but not H89. | Tyrosine | protein tyrosine kinase 2 beta | Homo sapiens |
| 5 | The results suggest that PAC1 regulates PYK-2 tyrosine phosphorylation in a calcium-dependent manner. | Tyrosine | protein tyrosine kinase 2 beta | Homo sapiens |